jueves, 24 de julio de 2025

PUBLICACIONES MAS RECIENTES





TRABAJOS PUBLICADOS EN REVISTAS, LIBROS Y CAPÍTULOS DE LIBRO Y EN ACTAS DE CONFERENCIA DEL CIPYP 

(SE MUESTRAN SOLO LAS PUBLICACIONES DESDE 2009)

 

PUBLICACIONES

Laser NIR irradiation enhances antimicrobial photodynamic inactivation of biofilms of Staphylococcus aureus.  Mamone L, Tomás R, Di Venosa G, Gándara L, Durantini E, Buzzola F, Casas A. Lasers in Surgery and Medicine (2024). En prensa.

Porfiria aguda intermitente: Presentación de caso. Varela L, Melito V, Guolo M, Caballero F, Goñi V, Martínez M del C, Pasman M, Paccioli V, Tomassi L, Buzaleh AM, Parera VE. Química Viva 23 (2) (2024).

Xenobiotics triggering Acute Intermittent Porphyria and their effect on mouse brain respiratory complexes Zuccoli J.R., Martínez M.d.C, Vallecorsa P.D., Buzaleh A.M. J. Xenobiot. 14(1) (2024) 308-319.

An Improved Technique for Genotyping the ABCB1 Gene Variant of Exon 21. Zuccoli J, Pagnota P, Melito V, Lavandera J, Parera V, Buzaleh AM. Methods Protoc 6 (2023) 53. https://doi.org/10.3390/mps6030053.

The Impact of Low-Level Benzalkonium Chloride Exposure on Staphylococcus spp. Strains and Control by Photoinactivation. Bonsaglia ECR, Calvo GH, Sordelli DO, Silva NCC, Rall VLM, Casas A, Buzzola F. Antibiotics (Basel) (2023) 12(8):1244. doi: 10.3390/antibiotics12081244.

Ras-transfected human mammary tumour cells are resistant to photodynamic therapy by mechanisms related to cell adhesion. Rodriguez, L, Di Venosa G, Rivas MA, Juarranz A, Sanz-Rodriguez, F, Casas A. Life sciences (2023) 314, 121287. doi: 10.1016/j.lfs.2022.121287

Hydrogen sulfide decreases photodynamic therapy outcome through the modulation of the cellular redox state. Calvo G, Céspedes M, Casas A, Di Venosa G, Sáenz D. Nitric oxide: biology and chemistry (2022) 125-126, 57–68.   doi: 10.1016/j.niox.2022.06.006

Mode of action of the sesquiterpene lactones estafietin and eupatoriopicrin on Trypanosoma cruzi. Elso OG, Puente V, Barrera P, Sosa-Escudero MA, Sülsen VP, Lombardo ME. Phytomedicine (2022) 96: Article 153900. Aceptado en Diciembre de 2021. https://doi.org/10.1016/j.phymed.2021.153900

Antiparasitic derivatives of the furoquinoline alkaloids kokusaginine and flindersiamine Valdez MB, Bernal Giménez DM, Fernández LR, Musikant AD, Ferri G, Saenz D, Di Venosa G, Casas A, Avigliano E, Edreira MM, Palermo J. Chem Med Chem (2022) doi: 10.1002/cmdc.202100784.

Photodynamic effect of protoporphyrin IX in gliosarcoma 9l/lacZ cell line. Fontana LC, Pinto JG, Vitorio GDS, Ferreira I, Pacheco-Soares C, Mamone LA, Strixino JF. Photodiagnosis Photodyn Ther. (2022) :102669. doi: 10.1016/j.pdpdt.2021.102669.

An increase in O-GlcNAcylation of Sp1 down-regulates the gene expression of pi class glutathione S-transferase in diabetic mice. Oliveri LM, Buzaleh AM, Gerez EN Biochem Biophys. Rep (2021) https://doi.org/10.1016/j.bbrep.2021.101049 doi: 10.1016/j.bbrep.2021.101049

Clinical, Biochemical and Genetic characterization of Acute Hepatic Porphyrias in a cohort of Argentine patients. Martinez M. del C, Cerbino GN, Granata B.X, Batlle A, Parera VE, Rossetti M.V. Mol. Gen. Genomic Med (2021) 9:e1059.1-7.

Synthesis and cytotoxicity evaluation of olivacine-indole hybrids tethered by alkyl linkers. Pis Diez CM, Céspedes M, Di Venosa G, Calvo G, Avigliano E, Casas A, Palermo J. Natural Product Research (2021) doi: 10.1080/14786419.2021.1880401.

Apoptotic cell death induced by dendritic derivatives of aminolevulinic acid in endothelial and foam cells co-cultures. Céspedes M, Saénz D, Calvo G, González M, MacRobert A, Battah S, Casas A, Di Venosa G. Photochemical and Photobiological Sciences (2021) doi: 10.1007/s43630-021-00025-x.

Novel meso-substituted porphyrin derivatives and its potential use in photodynamic therapy of cancer. Vallecorsa P, Di Venosa G, Ferreyra D, Ballatore MB, Mamone L, Sáenz D, Durantini E, Casas A. BMC Cancer (2021) doi: 10.1186/s12885-021-08286-6.

Photodynamic therapy of cutaneous T-cell lymphoma cell lines mediated by 5-aminolevulinic acid and derivatives. Vallecorsa P, Di Venosa G, Gola G, Sáenz D, Mamone L, MacRobert A, Ramirez J, Casas A. J. Photochem Photobiol, B: Biology (2021) doi: 10.1016/j.jphotobiol.2021.112244

Photosensitization of a subcutaneous tumour by the natural anthraquinone parietin and blue light" Mugas ML, Calvo G, Marioni J, Céspedes M, Martinez F, Vanzulli S, Sáenz D, Di Venosa G, Nuñez Montoya S, Casas A. Sci Reports (2021) 11(1):23820. doi: 10.1038/s41598-021-03339-z.

Role of ABCB1 and glutathione S‑transferase gene variants in the association of porphyria cutanea tarda and human immunodeficiency virus infection. Pagnota P, Lavandera J, Parera V, Rossetti MV, Melito V, Zuccoli JR, Buzaleh AM. Biomed. Rep. (2020) https://doi: 10.3892/br.2020.1398. Corresponding author: Buzaleh A.M.

Acute Intermittent Porphyria in a Man with Dual Enzyme Deficiencies. Cerbino GN, Abou Assali L, Varela L, Tomassi L, Batlle A, Parera VE, Rossetti M.V. Case Reports in Genetics-10/20- Pag 1-6.  Volume 2020, Article ID 8873219, 6 pages. https://doi.org/10.1155/2020/8873219

High level of haem precursors in AIP men carrying CYP2C9 1/ 2 haplotype. Abou Assali L, Gordillo DM, Cerbino G, Varela L, Parera VE, Rossetti MV. Eur J Mol Clin Med.1 11/2020.

Photodynamic inactivation mediated by 5-aminolevulinic acid of bacteria in planktonic and biofilm forms. Cervini Bohm G, Gándara L, Di Venosa G, Mamone L, Buzzola F, Casas A. Biochemical Pharmacology (2020) doi: 10.1016/j.bcp.2020.114016

Photosensitization of tumor cells mediated by parietin the natural anthraquinone parietin and blue light Mugas ML, Calvo G, Marioni J, Céspedes M, Martinez F, Sáenz D, Di Venosa G , Cabrera JL, Nuñez Montoya S, Casas A. J. Photochem Photobiol 214:112089 (2020) doi: 10.1016/j.jphotobiol.2020.112089.

Clinical uses of 5-aminolaevulinic acid in photodynamic treatment and photodetection of cancer: A review. Casas A. Cancer Lett.:490:165-173 (2020). doi: 10.1016/j.canlet.2020.06.008.

Bacterial viability after antimicrobial photodynamic therapy with Curcumin on multiresistant Staphylococcus aureus. Alves Freitas M, Correia Pereira A, Guerra Pinto J, Casas A, Ferreira-Strixino J. Fut. Microbiol. 14:739-748 (2019). doi: 10.2217/fmb-2019-0042.

Study of the relationship between variants of CYP2C9 enzyme and Acute Intermittent Porphyria manifestation. Abou Assali L, Gordillo DM, Cerbino GN, Varela LS, Batlle A , Parera VE, Rossetti MV. Int. J. Latest Res. Sci. Technol. 8(3):1-6 (2019).

Disaccharides obtained from carrageenans as potential antitumor agents. Calvo G, Cosenza V, Sáenz D, Navarro D, Stortz C, Céspedes M, Mamone L, Casas A, Di Venosa G. Sci Rep. 9:6654 (2019). doi: 10.1038/s41598-019-43238-y.

Synthesis, 2D-QSAR studies and Biological Evaluation of Quinazoline Derivatives as potent Anti-Trypanosoma cruzi Agents. Bollini M, Bruno AM, Niño ME, Casal JJ, Sasiambarrena LD, Valdez DAG, Battini L, Puente VR, Lombardo ME. Med Chem 15:265-276 (2019) doi: 10.2174/ 1573406414666181005145042

Trypanosoma cruzi mitochondrial dysfunction and its binding to thiol groups as primary targets of the sesquiterpene lactone deoxymikanolide mode of action.  Puente V, Laurella LC, Spina RM, Lozano E, Martino VS, Sosa MA, Sülsen VP, Lombardo M.E. Phytomedicine 56:27-34 (2019).

Impacto clínico de la investigación básica: Terapia antioxidante: Un nuevo enfoque en el tratamiento de la Enfermedad de Chagas. Puente VR, Lombardo ME. La Revista del Hospital de Clínicas. (2019). 

Synthesis and biological evaluation of new quinoline derivatives as antileishmanial and antitrypanosomal agents. Chanquia SN, Larregui F, Puente V, Labriola C, Lombardo E, García Liñares G. Bioorg Chem. 83:526-534 (2019) doi: 10.1016/j.bioorg.2018.10.053

Haplotype Analysis of Single Nucleotide Polymorphisms of CYP1A1 and CYP1A2 and its relationship with the Development of Porphyria Cutanea Tarda. Gordillo DM, Abou Assali L, Cerbino GN, Varela LS, Batlle A, Parera VW, Rossetti MV. Int J Latest Res Sci Techol 7(6):12-17 (2018).

One-step preparation of novel 1-(N-indolyl)-1,3- butadienes by base-catalysed isomerization of alkynes as an access to 5-(N-indolyl)- naphthoquinones C. Pis Diez M, Fernandez J, Di Venosa G, Casas A, Pis Diez R, Palermo J. RSC Adv. 8:35998 (2018). doi: 10.1039/C8RA05208E.

Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi.  Puente VR, Demaria AA, Frank FM, Batlle A, Lombardo ME. PLoS Negl Trop Dis (2018) 12:e0006764. doi: 10.1371/journal.pntd.0006764.

Studies of 4-arylthiazolylhydrazones derived from 1-indanones as Trypanosoma cruzi squalene epoxidase inhibitors by molecular simulations. Noguera GJ, Fabian LE, Lombardo E, Finkielsztein LM. Org Biomol Chem 16:8525-8536 (2018) doi: 10.1039/c8ob02310g.

Effects of volatile anaesthetics on heme metabolism in a murine genetic model of Acute Intermittent Porphyria. A comparative study with other porphyrinogenic drugs. Ruspini SF, Zuccoli JR, Lavandera JV, Martínez M del C, Oliveri LM, Gerez EN, Batlle A, Buzaleh AM. Biochim. Biophys. Acta (General Subjects) (2018) doi.org/10.1016/j.bbagen.2018.02.013

Enhancement of photodynamic inactivation of Staphylococcus aureus biofilms by disruptive strategies. Gándara L, Mamone L, Bohm G, Buzzola F, Casas A. Lasers Med Sci. 32:1757-1767 (2017) doi:10.1007/s10103-017-2253-3.

Synthesis and cytotoxicity evaluation of A-ring derivatives of cycloartanone. Zambrano E, Casas A, Di Venosa G, Uriburu N, Duran F, Palermo A. Phytochem. Lett. 21:200-205 (2017) doi: 10.1016/j.phytol.2017.06.021.

Reversal of the migratory and invasive phenotype of Ras-transfected mammary cells by photodynamic therapy treatment. Calvo G, Sáenz D, Simian M, Sampayo R, Mamone L, Vallecorsa P, Batlle A, Casas A, Di Venosa G.  J. Cell Physiol. 118:464-477 (2017). doi: 10.1002/jcb.25657.

Protective effect exerted by soil phosphorus on soybean subjected to arsenic and fluoride. Bustingorri C, Noriega G, Lavado R, Balestrasse K. Redox Report. 22(6):353–360 (2017).

Sae regulator factor impairs the response to photodynamic inactivation mediated by Toluidine blue in Staphylococcus aureus. Gándara L, Mamone L, Dotto C, Buzzola F, Casas A.  Photodiagnos. Photodyn. Ther. 16:136-141 (2016). doi: 10.1016/j.pdpdt.2016.09.005.

Synthesis of chemically diverse esters of 5-aminolevulinic acid for photodynamic therapy via the multicomponent Passerini reaction. Gola G, Di Venosa G, Sáenz D, Calvo G, Cabrera G, Casas A, Ramírez J. RSC Adv. 6, 89492-89498 (2016). doi: 10.1039/c6ra15832c.

Methods for the detection of reactive oxygen species employed in the identification of plant photosensitizers. Mamone L, Di Venosa G, Saenz D, Batlle A, Casas A.  Methods 109:73-80 (2016). doi: 10.1016/j.ymeth.2016.05.020.

Photodynamic inactivation of planktonic and biofilm growing bacteria mediated by a meso-substituted porphyrin bearing four basic amino groups. Mamone L, Ferreyra D, Gándara L, Di Venosa G, Vallecorsa P, Sáenz D, Calvo G, Batlle A, Buzzola F, Durantini E, Casas A. Photochem Photobiol B Biol 161:222-229 (2016). doi: 10.1016/j.jphotobiol.2016.05.026.

Thalidomide analogues: Tumor necrosis factor-alpha inhibitors and their evaluation as anti-inflammatory agents. Casal JJ, Bollini M, Lombardo ME, Bruno AM. Eur J Pharm Sci. 83:114–119 (2016).

Mode of Action of the Sesquiterpene Lactones Psilostachyin and Psilostachyin C on Trypanosoma cruzi. Sülsen VP, Puente V, Papademetrio D, Batlle A, Martino VS, Frank FM, Lombardo ME. PLoS One 11: e0150526 (2016) doi:10.1371/journal.pone.0150526.

Metabolismo del hemo: las dos caras de los efectos de la acumulación de precursores y porfirinas Rossetti MV, Buzaleh AM, Parera VE, Fukuda H, Lombardo ME, Lavandera J, Gerez EN,  Melito VA,  Zuccoli JR, Ruspini SF, Puente VR, Diez BA,  Teijo MJ,  Cerbino GN,  Varela LS, Guolo M, Batlle A.  Acta Bioquím Clín Latinoam 50(4): 547-573 (2016).

Haplotype study in Argentinean variegate porphyria patients. Granata B, Parera VE, Batlle A, Rossetti MV. Human Heredity 80(3):139-43 (2016). doi: 10.1159/000445749.

Aminolevulinic acid dendrimers in photodynamic treatment of cancer and atheromatous disease. Rodriguez L, Vallecorsa P, Battah S, Di Venosa G, Calvo G, Mamone L, Sáenz D, Gonzalez M, Batlle A, MacRobert A, Casas A. Photochem Photobiol Sci 14:1617-1627 (2015)  doi: 10.1039/c5pp00126a.

The role of cytoskeleton and adhesion proteins in the resistance to Photodynamic Therapy. Possible therapeutic interventions. Di Venosa G,  Perotti C, Batlle A, Casas A. Photochem. Photobiol. Sci.14:1451-64 (2015) doi: 10.1039/c4pp00445k.

The Use of Dipeptide Derivatives of 5-Aminolaevulinic Acid Promotes Their Entry to Tumor Cells and Improves Tumor Selectivity of Photodynamic Therapy. Di Venosa G, Vallecorsa P, Giuntini F, Mamone L, Batlle A, Vanzuli S, Juarranz A, MacRobert A, Eggleston I, Casas A. Mol Cancer Ther. 14:440-451 (2015). doi: 10.1158/1535-7163.MCT-13-1084.

QSAR study and conformational analysis of 4-arylthiazolylhydrazones derived from 1-indanones with anti-Trypanosoma cruzi activity Noguera G.J., Fabian L.E., Lombardo E. & Finkielstein L. Eur J Pharm Sci. (2015) 78:190-197.

Acute Intermittent Porphyria in Argentina. An Update. Cerbino GN, Gerez EN, Varela LS, Melito VA,  Parera VE, Batlle A, Rossetti MV. Biomed Res Int Volume 2015, Article ID 946387 (2015) http://dx.doi.org/10.1155/2015/946387.

Experimental Protoporphyria: Effect of bile acids on liver damage induced by griseofulvin. Martinez M del C, Ruspini SF, Afonso SG, Meiss R, Buzaleh AM, Batlle, A. Biomed Res Int  (Article 436319) (2015) 1-10. http://dx.doi.org/10.1155/2015/436319.

Characterization of three Variegate Porphyria mutations using a minigene approach. Granata BX, De Conti L, Baralle M, Parera VE, Rossetti MV. J Inh Metab Dis 20:39-44 (2015) doi: 10.1007/8904_2014_388.

Photoprotective Effect of the Plant Collaea argentina against Adverse Effects Induced by Photodynamic Therapy. Mamone L, Sáenz D, Vallecorsa P, Batlle A, Casas A, Di Venosa G. Int. J. Photoenergy, Volume 2014,Article ID 436463. (2014)  doi: 10.1155/2014/436463.

The natural flavonoid silybin improves the response to Photodynamic Therapy of bladder cancer cells. Gandara L, Sandes E, Di Venosa G, Prack Mc Cormick B, Rodriguez L, Mamone L, Batlle A, Eiján A, Casas A. J. Photochem. Photobiol. B Biol. 33:55-64 (2014). doi: 10.1016/j.jphotobiol.2014.03.006.

Pleiotropic effects of 5-aminolevulinic acid in mice brain.  Lavandera J, Rodríguez J, Ruspini S, Meiss R, Zuccoli J, Martínez MC, Gerez E, Batlle A, Buzaleh AM. Biochem Cell Biol (2016) Doi: 10.1139/bcb-2015-0094.

Porphyria Cutanea Tarda and HFE Gene Mutations in Argentina. Colombo F, Martínez J, Varela L, Gerez E, Méndez M, Batlle A, Rossetti MV, Parera V. Br J Med Med Res 4(8):1691-1700 (2014). 

Photodynamic inactivation of Gram-positive bacteria employing natural resources. Mamone L, Di Venosa G, Gándara L, Sáenz D, Vallecorsa P, Schickinger S, Rossetti MV, Batlle A, Buzzola F, Casas A. J Photochem Photobiol B. 133:80-89 (2014) doi:10.1016/j.jphotobiol.2014.03.003.

Indole acetic acid is responsible for protection against oxidative stress caused by drought in soybean plants: The role of heme oxygenase induction. Lopez Lecube M, Noriega G, Santa Cruz D, Tomaro M. L, Batlle A., Balestrasse K. Redox Report. 19(6):242-250 (2014).

Light fractionated ALA-PDT enhances therapeutic efficacy in vitro; the influence of PpIX concentration and illumination parameters. de Bruijn H, Casas A, Di Venosa G, Gandara L, Sterenborg H, Batlle A, Robinson D. Photochem Photobiol Sci. 12:241-245 (2013). doi: 10.1039/c2pp25287b.

Protective action of antioxidants on hepatic damage induced by griseofulvin. Martinez M del C, Afonso SG, Buzaleh AM, Batlle A.TSWJ: Pharmacology Article ID 982358, 1-8 (2014) http://dx.doi.org/10.1155/ 2014/982358.

Cytochrome P450 expression in mouse brain: specific isoenzymes involved in phase I metabolizing system of porphyrinogenic agents in both microsomes and mitochondria. Lavandera J, Ruspini S, Batlle A, Buzaleh AM. Biochem Cell Biol 92:1-6 (2014) http://dx.doi.org/10.1139/bcb-2014-0088.

Trypanocidal activity of tioamide-sustituted imidazoisoquinolinones: Electrochemical properties and biological effects. Frank F, Ciccarelli A, Bollini M, Bruno A, Batlle A, Lombardo E. Evid. Based Complement. Alternat. Med. 2013:945953 (2013).

An Odd Case of Heteroallelic Acute Intermittent Porphyria in the Argentinean Population. Piñeiro Pauwels MB, Gerez EN, Martínez MC, Melito VA, Estela Parera VE, Batlle A, Rossetti MV. Cell Mol Biol 59(Supp):OL1855-OL1860 (2013).

Heme metabolism, oxidative and nitrosative markers in a mouse model of hemochromatosis. Effect of isoflurane, ethanol and 5-aminolevulinic acid. Buzaleh AM, Moreno-Carralero MI, Méndez M, Batlle A, Enríquez de Salamanca R, Morán-Jimenez MJ. J. Pathol. Res. 2:15-20 (2013) http://dx.doi.org 10.9735/0976-8068.

Molecular analysis of the UROD gene in 17 Argentinean patients with familial porphyria cutanea tarda: Characterization of four novel mutations. Méndez M, Rossetti MV, Gómez-Abecia S, Morán-Jiménez MJ, Parera V, Batlle A, Enríquez de Salamanca A. Mol Gen Metab 105(4):629-633 (2012).

Combined chemotherapy and ALA-based photodynamic therapy in leukemic murine cells. Diez B, Ernst G, Teijo MJ, Batlle A, Hajos S, Fukuda H. Leuk Res. 36(9):1179-1184 (2012) doi: 10.1016/j.leukres.2012.04.027.

Functional associations of genetic variants involved in the clinical manifestation of erythropoietic protoporphyria in the Argentinean Population. Colombo FP, Rossetti MV, Mendez M, Martínez JE, Enriquez de Salamanca R, Batlle A, Parera VE. J Eur Eur Dermatol Venn (2012) Doi:10.1111/j.1468-3083.2012.04566.x 

Changes in actin and E-cadherin expression induced by 5-aminolevulinic acid photodinamic therapy in normal and Ras-transfected human mammary cell lines. Di Venosa G, Rodriguez L, Mammone L, Gándara L, Rossetti MV, Batlle A, Casas A. J Photochem Photobiol B: Biology 106:47-52 (2012).

Functional characterization of five protoporphyrinogen oxidase missense mutations found in Argentinean Variegate patients. Méndez M, Granata BX, Morán Jiménez MJ, Parera VE, Batlle A, Enríquez de Salamanca R, Rossetti MV. J Inh Metab Dis 4:91-97 (2012)  Doi 10.1007/8904.77.

Synthesis and biological evaluation of some novel 1-indanone thiazolylhydrazone derivatives as anti-Trypanosoma cruzi agents. Caputto ME, Cicarelli A, Moglione A, Moltrasio G, Lombardo E, Finkielsztein L. Eur J Med Chem 55:155-163 (2012).

Anti-parasitic effect of vitamin B12 on Trypanosoma cruzi. Antimicrob. Ciccarelli A, Frank F, Puente V, Malchiodi E, Batlle A, Lombardo ME.  Agents Chemother. 56:5315-5320 (2012).
ALAS-1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice. Oliveri LM, Davio C, Batlle A, Gerez EN. BJ Metabolism 442(2): 303-310 (2012).

Heme Oxygenase is involved in the protection exerted by jasmonic acid against cadmium stress in soybean roots. Noriega, G., Cruz, D.S., Batlle, A., Tomaro, M., Balestrasse, K. J. Plant Growth Reg 31:79-89 (2012).

The role of salicylic acid in the prevention of oxidative stress elicited by cadmium in soybean plants. Noriega G, Caggiano E, Lecube ML, Cruz DS, Batlle A, Tomaro M, Balestrasse KB. Biometals 25:1155-1165 (2012).

Identification of CYP3A5 and CYP2B6 Polymorphisms in Porphrya Cutanea Tarda associated to human Inmunodeficiency virus. Lavandera JV, Parera VE, Rossetti MV, Batlle A, Buzaleh AM. J Clin Exp Dermatol Res (2011) http://dx.doi.org/10.4172/2155-9554.S4-001.

Mechanisms of resistance to Photodynamic Therapy. Casas A. Di Venosa G, Hasan H, Batlle A. Curr Med Chem 18:2486-515 (2011). DOI: 10.2174/092986711795843272.

Cytotoxic effects of Argentinian plant extracts on tumor and normal cell lines.  Mamone L, Di Venosa G, Valla J, Rodriguez L, Gándara L, Batlle A, Heinrich M, Juarranz A, Sanz- Rodriguez F, Casas A. Cell Mol Biol (Noisy-le-grand) 57 Suppl:OL1487-99 (2011).

Mice brain nitric oxide synthase response induced by anaesthetics and other porphyrinogenic drugs  system: another target for the action of porphyrinogenic agents. Lavandera J, Batlle A, Buzaleh A.M. Drug  Metab. Lett. 5:25-29 (2011).

Identification of CYP3A5 and CYP2B6 Polymorphisms in Porphyria Cutanea Tarda Associated to Human Immunodeficiency Virus. Lavandera J, Parera V, Rossetti MV, Batlle A, Buzaleh AM. J Clin Exp Dermatol Res S:4 (2011) http://dx.doi.org/10.4172/2155-9554.S4-001

Possible involvement of stress hormones and hyperglycaemia in chronic mild stress-induced impairment of immune functions in diabetic mice. Rubinstein MR, Cremaschi GA, Oliveri LM, Gerez EN, Wald MR and Genaro AM (2010) Stress 13(5):384-391.

Heme oxygenase-1 is involved in the protection against chilling exerted by low ALA concentrations in soybean plants. Balestrasse KB, TomaroML, Batlle A, Noriega GO. Phytochemistry 71(17-18):2038-2045 (2010).

Comparison of liposomal formulations of ALA Undecanoyl ester for its use in photodynamic therapy. Di Venosa G, Hermida L, Fukuda H, Defain MV, Rodriguez L, Mamone L, MacRobert A, Casas A, Batlle A. J Photochem Photobiol B., 96:152-158 (2009). doi: 10.1016/j.jphotobiol.2009.06.001.

Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy. Rodriguez L, de Bruijn HS, Di Venosa G, Mamone L, Robinson D, Juarranz A, Batlle A, Casas A. J Photochem Photobiol B. 96:249-254 (2009). doi: 10.1016/j.jphotobiol.2009.07.001.

Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy. Casas A, Battah S, Di Venosa G, Dobbin P, Rodriguez L, Fukuda H, Batlle A, Macrobert A. J Control. Release 135:136-143 (2009). doi: 10.1016/j.jconrel.2009.01.002.

The very first description of a patient with hepatoerythropoietic porphyria in Argentina. Biochemical and molecular studies. Granata BX, Parera VE, Melito VA, Teijo MJ, Batlle AM, Rossetti MV. Cell Mol Biol 55(1):61-65 (2009)

HFE Gene mutations in patients with altered iron metabolism in Argentina. Rossetti MV, Méndez M, Afonso SG, Gerez EN, Batlle A, Muñoz A, Parera VE. Cell Mol Biol 55(2):31-35 (2009).

Novel null–allele mutations and genotype-phenotype correlation in Argentinean patients with Erythropoietic Protoporphyria. Parera VE, Koole RH, Minderman G, Rossetti MV, Batlle A, De Rooij F. Mol Med 15(11-12):425-431 (2009).

Induction of Hepatic Aminolevulinate Acid Synthetase Activity by Isoflurane in a Genetic Model for Erythropoietic Protoporphyria. Buzaleh AM, Morán-Jiménez MJ, García-Bravo M, Sampedro A, Batlle A., Enríquez de Salamanca R, Fontanellas A. Cell. Mol. Biol.  55 (1):38-44 (2009).

Glutamatergic System: another target for the action of porphyrinogenic agents. Lavandera J, Fossatti M, Azcurra J, Batlle A, Buzaleh AM. Cell Mol Biol 55 (1):23-28 (2009).

Hepatic damage and oxidative stress induced by griseofulvin in mice. Martinez M del C, Afonso SG, Meiss R, Buzaleh AM, Batlle A. Cell. Mol. Biol 55(2):121-133 (2009).

Sevoflurane: its action on heme metabolism and Phase I drug metabolizing system. Sampayo R, Lavandera J, Batlle A, Buzaleh AM. Cell Mol Biol  55(2):134-140 (2009).

Heme oxygenase contributes to alleviate salinity damage in Glycine max L. leaves. Zilli CG, Santa-Cruz DM, Yannarelli GG, Noriega GO, Tomaro ML, Balestrasse KB. Int J Cell Biol 2009:848516 (2009) doi:10.1155/2009/848516.

Ros production by endogenously generated Protoporphyrin IX in murine leukemia cells. Diez B, Cordo Russo R, Teijo MJ, Hajos S, Batlle A, Fukuda H. Cell Mol Biol (Noisy-le-grand). 55(2):15-19 (2009).

Endogenous and exogenous porphyrins as photosensitizers in the Hep-2 human carcinoma cell line. Alvarez MG, Milanesio M, Rivarola V, Durantini E, Batlle A, Fukuda H. Cell Mol Biol (Noisy-le-grand). 55(2):8-14 (2009).

 

Libros

Factores limitantes en la inducción de muerte celular por Terapia fotodinámicacon ALA en cultivos bi y tridimensionales de células de adenocarcinoma de pulmón Teijo MJ, Batlle A, Fukuda H. Editorial Académica Española, 2017. p. 47. ISBN 978-3-639-47221-9.

Búsqueda de nuevos fotosensibilizantes y principios activos a partir de plantas regionales para su uso en el tratamiento del cáncer. Mamone L, Di Venosa G, Casas A. Editorial académica española, Berlin (2013), ISBN: 978-3-8465-7926-8.

Respuesta a la Terapia Fotodinámica empleando un láser de 635 nm. Rodriguez L, Batlle A, Casas A. Editorial académica española, 2012. p. 53. ISBN 978-3-8484-6140-0. Berlín

 

Capítulos de Libro

Study on the role of ABCB1 and glutathione S-transferase gene variants in the association of Porphyria Cutanea Tarda and human immunodeficiency virus infection. Pagnotta P, Melito V, Lavandera J, Buscalia ML, Parera VE, Rossetti MV, Zuccoli J & Buzaleh AM. New Frontiers in Medicine and Medical Research, Vol. 4, Chapter 21, pp. 149-169. Editorial: BPInternational, Ciudad: Londres (2021) DOI: 10.9734/bpi/nfmmr/v4/10963D

Diabetes and Pi Class Glutathione S-Transferase. Oliveri LM, Mora Milena S, Buzaleh AM, & Gerez EN. New Innovations in Chemistry and Biochemistry. Vol. 7, Chapter 12, pp. 135-173. Editorial: BPInternational, Ciudad: Londres (2022) DOI: 10.9734/bpi/nicb/v7/2250C.

Hepatic Damage Induced by Griseofulvin as a Murine Model of Protoporphyia. Effect of Antioxidants. Martínez M del C, Afonso SG, Batlle A & Buzaleh AM. Innovations in Science and Technology Vol. 6, Chapter 5, pp. 75-90. Editorial: BPInternational, Ciudad: Londres (2022) DOI: 10.9734/bpi/ist/v6/12456D.

Mechanisms of Resistance to Photodynamic Therapy: An Update (Chapter 2). Casas A, Perotti C, Di Venosa G, Batlle A. En Resistance to Photodynamic Therapy in Cancer, Resistance to Targeted Anti-Cancer Therapeutics 5 (2015) pp 29-63, Springer International Publishing Switzerland. V. Rapozzi, G. Jori (eds.), DOI 10.1007/978-3-319-12730-9_2.

In vitro and in vivo 5-Aminolevulinic acid-based photodynamic therapy in sensitive and drug resistant leukemic murine cells. Diez B, Hajos S; Meiss R, Ernst G, Teijo MJ, Batlle A, Fukuda H, Hauppauge NY: Nova Science Publishers, 2015. p. 173-191. ISBN 978-1-63463-857-9.

Studies on extracts of Argentinean plants: cytotoxic tumoral activity per se and as photosensitizers in photodynamic of cancer.  Batlle A, Mamone L, Casas A, Rodríguez L, Di Venosa G. En "In the hope of going over the present Clinical PD and PDT". A Symposium Book in "Pacifichem 2010", General Editors N. Miyoshi and Pottier, R.H., Chaper 1: (2011) pp 4 - 22. Publisher, Sankeisha Co., Ltd, Chumaru-cho, Kita-ku, Nagoya, Aichi, Japan. ISSBN978-4-88361-883-5-C3047

Drogas de abuso. Una falsa y efímera felicidad? Wolansky M, Rossetti MV. Asociación Química Argentina (Ed, 2011. p. 347-372. ISBN 978-987-99428-3-3

Porphyrias and associated pathologies. Biochemistry and Molecular Biology, Preface part I. Batlle A, Rossetti, MV, Noisy Le Grand: Cell Mol Biol edition, 55 (I) (2009) p. 1-5.

Porphyrias and associated pathologies. Biochemistry and Molecular Biology, Preface part II. Batlle A, Rossetti, MV. Noisy Le Grand: Cell Mol Biol edition, 55 (II) (2009) p. 1-7.

 

Publicaciones en Actas de Conferencia (últimos 10 años)

 

Acute Intermittent Porphyria onset: Bioinformatic and genetic analysis of porphyrinogenic xenobiotics and drugs transporter system. Pagnotta P, Melito V, Zuccoli J, Parera V, Buzaleh AM. BMJ Open Gastroenterology 11 (Suppl 1) (2024) Res 4159.

Hemin treatment during attacks in Argentinean patients with acute porphyrias.  Melito V, Varela L, Martínez M del C, Goñi V, Orquera C, Baccaro F, Herrando S, Merlo G, Sánchez Gelós D, Pasman M, Buzaleh AM, Tomassi L, Parera V. BMJ Open Gastroenterology 11 (Suppl 1) (2024) Res 4167.

Early, quick and accurate identification of acute porphyrias in health centers: PBG reagent. Martínez M del C, Melito V, Caballero F, Guolo M, Lucero JB, Schlender W, Parera V, Buzaleh AM. BMJ Open Gastroenterology 11 (Suppl 1) (2024) Res 4123.

Hepatic porphyrias onset. The role of NR1I2 gene variants. Zuccoli J, Melito V, Varela L, Pagnotta P, Parera V, Buzaleh AM. BMJ Open Gastroenterology 11 (Suppl 1) (2024) Res 4164.

Management of hereditary coproporphyria: a case report of a new pathogenic variant, highlighting the significance of hemin therapy and maintenance treatment compliance. Varela L, Melito V, Buzaleh AM, Parera V, Di Pierro E. BMJ Open Gastroenterology 11 (Suppl 1) (2024) Res 4165.

Understanding variegate porphyria in a HIV patient: a detailed case study. Varela L, Melito V, a Caballero F, Guolo M, Goñi V, Winitzky P, Agosta M, Pasman M, Buzaleh AM, Tomassi L, Parera VE. BMJ Open Gastroenterology 11 (Suppl 1) (2024) Res 4166.

Porfiria Aguda Intermitente: Implicancias de las variantes del transportador ABCG2. Yun S, Santillán T, Melito V, Pagnotta P, Varela L, Parera V, Buzaleh AM, Zuccoli J. J Basic Appl Genetics XXXIV Issue 1 (suppl.) (2023) 91, Res FG2.

Análisis bioinformático exploratorio sobre el rol de variantes en el gen NR1I2 en la manifestación de la Porfiria Aguda Intermitente. Pagnotta P, Zuccoli J, Melito V, Parera V, Buzaleh AM. J Basic Appl Genetics XXXIV Issue 1 (suppl.) (2023) 92, Res FG3.

Actualización de las variantes patogénicas en Porfiria Aguda Intermitente en la población argentina. Varela L, Buzaleh AM, Parera V. J Basic Appl Genetics XXXIV Issue 1 (suppl.) (2023) 119, Res GH2.

Effect of a diet enriched in olive oil in a knockout mouse model of Acute Intermittent Porphyria. Martinez M del C, Zuccoli J, Oliveri L, Mora S, Buzaleh AM, Gerez E. Medicina 83 (Supl V) (2023) 131, Res 183.

Analysis of the role of NR1I2 gene variants in Hepatic Porphyrias onset. Martínez Yucovsky K, Moltrasio I, Woo E, Santillán T, Yun S, Melito V, Varela L, Parera V, Buzaleh AM,  Zuccoli J. Medicina 83 (Supl V) (2023) 115, Res 135.

Manifestation of Acute Intermittent Porphyria: Bioinformatics analysis of the NR1L2 gene. Pagnotta P, Zuccoli J, Melito V, Parera V, Buzaleh AM. Medicina 83 (Supl V) (2023) 128, Res 428.

An overview of pathogenic variants in Acute Intermittent Porphyria in Argentina. Varela L, Caballero A, Guolo M, Buzaleh A, Parera V. Medicina 83 (Supl V) (2023) 115, Res 134.

Effect of serum from patients with Acute Intermittent Porphyria ON delta-Aminolevulinic acid synthase 1 protein expression in C3A hepatoma cells. Mora S, Oliveri L, Parera V, Buzaleh AM, Gerez. Medicina 83 (Supl V) (2023) 94, Res 69.

Combined treatment of NIR radiation and photodynamic inactivation in an in vivo model of S. aureus infection. Tomás R, Di Venosa G, Buzzola F, Casas A, Mamone L. Medicina 83 (Supl V) (2023) 128, Res 173.

Batista J, Calvo G, Navarro D, Sáenz D, Romina Cingolani2, Carlos Stortz2, Adriana Casas1, Gabriela Di Venosa1. New results on K-carrabiose as potential antitumor agent. Medicina 83 (Supl V) (2023) 181, Res 340.

Abordaje genético de las Porfirias: Complementación mediante eluso de bases de datos. Pagnotta P, Zuccoli J, Melito V, Buscalia ML, Parera V, Buzaleh AM. J. Basic Appl. Genetics XXXIII Issue 2 (suppl.) (2022)114, Res GH11.

Porfiria Cutánea Tardía en Argentina. Varela L, Méndez M, Cerbino G, Colombo F, Melito V, Buzaleh AM, Rossetti VE, Parera V. J Basic Appl Genetics XXXIII Issue 2 (suppl.) (2022) 113, Res. GH9.

Porphyria Cutanea Tarda in Argentina. An update. Varela L, Méndez M, Cerbino G, Colombo F, Melito V, Buzaleh AM, Parera V. Medicina 82 (Supl V) (2022) 130, Res 148.

Influencia de la variante NM_004827.3(ABCG2):c.34G>A (p.Val12Met) del gen ABCG2 en el desencadenamiento de la Porfiria Cutánea Tardía en individuos infectados con VIH. Buscalia ML, Melito V, Pagnotta P, Parera V, Buzaleh AM, Zuccoli J.  J Basic Appl Genetics XXXIII Issue 2 (suppl.) (2022) 113, Res GH10.

Photodynamic inactivation from ALA, on bacterial infections and skin wounds in an in vivo mouse model. Tomás R, Di Venosa G, Buzzola F, Casas A, Mamone L. Medicina 82 (Supl V) (2022) 163, Res 259.

Bioinformatic complementation of the role of genetic variants in the manifestation of Porphyrias. Pagnotta P, Buscalia ML, Zuccoli J, Melito V, Parera V, Buzaleh AM. Medicina 82 (Supl V) (2022) 92-93, Res 28(2022).

Acute Intermittent Porphyriaas a risk factor for hepatocellular carcinoma. First case in Argentina. Melito V, Varela L, Antinucci F, Brutti J, Maurette R, Tomassi L, Buzaleh AM, Parera V, Anders M. Medicina 82 (Supl V) (2022) 194, Res 363.

Acute Intermittent Porphyria: Involvement of ABCG2 transporter variants. Santillan T, Yun S, Zuccoli J, Buscalia ML, Varela L, Melito, V, Buzaleh AM.  Medicina 82 (Supl V) (2022) 130, Res 151.

Porphyrias during SARS-CoV-2 pandemic. A retrospective analysis. Melito V, Goñi V, Caballero A, Guolo M, Winitzky P, Varela L, Noriega G, Muramatsu H, Buzaleh AM, Parera V. Medicina 81 (Supl) (2021) 109, Res 132.

The use of light as an approach to control the growth of Staphylococcus aureus resistant strains. Sebastián T, Quiroga E, Di Venosa G, Buzzola F, Casas A, Mamone L. Medicina 81 (Supl) (2021) 71, Res 6.

Role of variants of ABCG2 GENE IN the triggering of Porphyria Cutanea Tarda in HIV-infected individuals. Buscalia ML, Zuccoli J, Melito V, Parera V, Buzaleh AM. Medicina 81 (Supl) (2021) 176, Res 352.

Effect of human serum on the expression levels of the 5-aminolevulinate synthetase 1 protein inC3A hepatoma cells. Mora S, Parera V, Oliveri L, Rossetti MV, Buzaleh AM, Gerez E.  Medicina 81 (Supl) (2021) 250, Res 598.

Characterization of a genetic murine model of Acute Intermittent Porphyria. An over time study. Martínez M del C, Zuccoli J, Ruspini S, Buzaleh AM. Medicina 81 (Supl) (2021) 177, Res 356.

Gordillo D, Abou Assali L, Cerbino G, Varela L, Parera V, Rossetti MV. Variantes genéticas del CYP2E1 y su relación con el desarrollo de la Porfiria Cutánea Tardía. J. Basic Appl. Genetics Vol XXXI Suppl 1 (2020) 85.

Variantes genéticas en ABCB1 y GST: Implicancia en eldesencadenamiento de la Porfiria Aguda Intermitente. Pagnotta P, Manrique Bojorquez N, Rossetti MV, Melito V, Buzaleh AM, Zuccoli J. J. Basic Appl. Genetics Vol XXXI Suppl. 1 (2020) 85.

The role of NM_004827.3:c.421C>A variant of ABCG2 gene in the triggering of Porphyria Cutanea Tarda in HIV-infected individuals. Buscalia ML, Zuccoli J, Melito V, Rossetti MV, Parera V, Buzaleh AM. Medicina 80 (Supl) (2020) 76, Res 103.

Insulin-like growth factor type 1 in patients with Acute Intermittent Porphyria and its relationship with heme biosynthesis intermediates. Mora SM, Oliveri LM, Calcagno M, Parera V, Rossetti MV, Gerez E. Medicina 80 (Supl) (2020) 78, Res 178.

Genotipificación de la variante c.421C>A del gen BCRP. Rol en el desencadenamiento de la Porfiria Cutánea Tardía en individuos infectados con VIH. Zuccoli J, Buscalia ML, Melito V, Parera V, Buzaleh AM. J Basic Appl Genetics XXXI Suppl. 1 (2020) 84.

Implication of glutathione S-transferases gene variants on Acute Intermittent Porphyria onset. Pagnotta P, Zuccoli J, Manrique Bojorquez N, Parera V, Rossetti MV, Batlle A, Melito V, Buzaleh AM. Medicina 79 Supl IV (2019) 96-97, Res 902

Study of the glycaemic and lipid profile in an Argentine population with Acute Intermittent Porphyria under a high-carbohydrate diet. Mora S, Oliveri L, Medina N, Calcagno M del L, Parera V, Rossetti MV, Gerez E. Medicina 79 Supl IV (2019) 158, Res 562.

Porphyrinogenic agents affect mitochondrial function in a mousemodel of Acute Intermittent Porphyria. Zuccoli J, Martínez M del C, Ruspini S, Batlle A, Buzaleh AM. Medicina 79 Supl IV (2019) 159-160, Res 937.

Photodynamic inactivation of gram positive and gram negative bacterias by the aminoporphyrin A4 and A4+. Ghio L, Mora J, Álvarez MG, Durantini E, Lombardo ME, Martínez M del C. Medicina 79 Supl IV (2019) 128, Res 948.

Biosynthesis of 5-aminolevulic acid in Trypanosoma cruzi. Puente V, Martínez M del C, Abou Assali, Benlolo M, Bontempi E, Lombardo ME. Medicina 79 Supl IV (2019) 127, Res 872.

Mode of action of the sesquiterpene lactone eupatoriopicrin on Trypanosoma cruzi. Orlando G, Puente V, Barrera P, Sosa Escudero M, Sülsen V, Lombardo ME.  Medicina 79 Supl IV (2019) 187, Res 886.

Temiño V, Rossetti MV, Gerez E. Porphyrinogenicity of drugs in Acute Intermittent Porphyria: are the CYP-450 polymorphisms the answer? Medicina 79 Supl IV (2019) 93, Res 560.

A higher level of O-glucocylation of sp1 down regulates gene expression of pi class glutathione s-transferase in diabetic mice. Oliveri L, Mora S, Zuccoli J, Buzaleh AM, Gerez E. Medicina 78 Supl III (2018) 216, Res 520.

Cytochrome P450 isoenzymes single nucleotide polymorphisms (SNPS) are really involved in Porphyria Cutanea Tarda? Gordillo D, Abou Assali L, Cerbino G, Batlle A, Varela L, Parera V, Rossetti MV. Medicina 78 Supl III (2018) 198, Res 457.

Derivados del ácido 5-aminolevulínico en el tratamiento fotodinámico del cáncer diseminado de ovario: modelos in vitro e in vivo. Orlando C, Céspedes M, Calvo G, Gola G, Ramirez J, Di Venosa G, Saenz D, Casas A. Revista del Hospital de Clínicas, UBA.

Céspedes M, Calvo G, Cosenza V, Sáenz D, Navarro D, Storzt C, Casas A, Di Venosa G.  Disacáridos obtenidos a partir de carragenanos como potenciales agentes antitumorales. Revista del Hospital de Clínicas, UBA (2018).

Local anaesthesia and Porphyria. Is Totalcaine forte a safe drug for porphyric patients? Mikulskyj SJ, Scolnik OS, Carabajal Waldhuter T, Martinez M del C, Zuccoli J, Buzaleh AM. Medicina 78 Supl III (2018) 190-191, Res 429.

MDR1 polymorphims and Acute Intermittent Porphyria. Manrique Bojorquez N, Zuccoli J, Pagnotta P, Parera V, Rossetti MV, Batlle A, Melito V, Buzaleh AM. Medicina 78 Supl III (2018) 197, Res 452.

Porfiria Aguda Intermitente y agentes porfirinogénicos: alteraciones mitocondriales en encéfalo. Zuccoli J, Martinez M del C, Ruspini S, Batlle A, Buzaleh AM. Revista del Hospital de Clínicas (2018) Res 0437.

Mutación de novo en Porfiria Aguda Intermitente en un paciente con Porfiria Cutánea Tardía Hereditaria. Cerbino GN, Abou Assali L, Varela L, Guolo M, Batlle A, Parera VE, Rossetti MV. Revista del Hospital de Clínicas, UBA, 2018.

New results about the relationship between CYP2C9 SNPS and Acute Intermittent Porphyria manifestation. Abou Assali L, Gordillo D, Cerbino G, Varela L, Batlle A, Parera V, Rossetti MV. Medicina 78 Supl III (2018) 197, Res 454.

Porfiria Cutánea Tardía e Infección por el virus de Inmunodeficiencia Adquirida. Melito, V. Rossetti, MV, Batlle A, Parera V. Revista del Hospital de Clínicas, UBA (2018).

Estudiar el rol de la variante 2 del CYP2C9 en la manifestación de la Porfiria Aguda Intermitente. Abou Assali L, Gordillo D, Cerbino GN, Varela L, Batlle A, Parera V, Rossetti MV. Revista del Hospital de Clínicas, UBA (2018).

Polimorfismos del gen de Resistencia a Multidrogas MDR1 en familias con Porfiria Aguda Intermitente.  Manrique Bojorquez N, Zuccoli J, Pagnotta P, Parera V, Rossetti MV, Batlle A, Melito V, Buzaleh AM. Revista del Hospital de Clínicas (2018) Res.0185.

Rol de las isoenzimas de loscitocromos CYP1A1 y CYP1A2 en el desencadenamiento de la Porfiria Cútanea Tardía. Gordillo D, Abou Assali L, Cerbino G, Varela L. Batlle A, Parera V, Rossetti MV. Revista del Hospital de Clínicas de Buenos Aires, UBA (2018).

Rol del pigmento estafiloxantina en la fotoinactivación de Staphylococcus aureus. Diaz R, Lombarte Serrat A, Saenz D, Calvo G, Suligoy M, Sordelli D, Casas A, Buzzola F. Revista del Hospital de Clínicas, UBA (2018).

Rol de los Polimorfismos del gen MDR1 en el desencadenamiento de la Porfiria Cutánea Tardía en individuos con VIH. Pagnotta P, Zuccoli J, Lavandera J, Parera V, Rossetti MV, Batlle A, Buzaleh AM, Melito V. Revista del Hospital de Clínicas, UBA (2018) Res 0499.

Terapia fotodinámica en el tratamiento de lesiones ateroscleróticas utilizando derivados de dendríticos del Ácido 5-Aminolevúlico: estudios in vitro. Calvo G, Céspedes M, Sáenz D, Jerez Pellegrino T, Vallecorsa P, Batlle A, Casas A, Di Venosa G. Revista del Hospital de Clínicas, UBA (2018).

Role of Glutathione S-Transferase gene polymorphismsin the onset of Porphyria Cutanea Tarda in HIV infected individuals. Pagnotta P, Melito V, Parera V, Rossetti MV, Batlle A, Buzaleh AM, Zuccoli J. Medicina 78 Supl III (2018) 197, Res 453.

Estudio de cuatro nuevos derivados del 5-ALA en el tratamiento fotodinámico de células de linfoma cutáneo T. Vallecorsa P, Di Venosa G, Saenz D, Calvo G, Gola G, Ramirez J, Batlle A, Casas A. Revista del Hospital de Clínicas, UBA (2018).

Fotoinactivación de cultivos planctónicos y biopelículas bacterianas empleando acido 5-aminolevulínico. Jerez Pellegrino T, Cervini Böhm G, Di Venosa G, Sáenz D, Calvo G, Céspedes M, Buzzola F, Casas A. Revista del Hospital de Clínicas, UBA (2018).

Clinical, biochemical and genetic characterization of acute hepatic Porphyrias in a cohort of Argentinean patients. Martinez M del C, Cerbino N, Granata B, Batlle A, Parera V, Rossetti MV Congreso. Medicina 78 Supl III (2018) 196, Res 451.

Prooxidant and antioxidant effect of vitamin C on Trypanosoma cruzi.Puente V; Demaría MA; Batlle A; Lombardo ME. Medicina 77 (2017), Supl 1, 512, Res 1755.

Effect of fetal bovine serum on delta aminolevulinic acid synthase expression in C3A hepatoma cells. Mora León S, Oliveri L, Wald M, Rossetti MV, Gerez E. Medicina 77 (2017) Supl 1, 154, Res 301.

Studies of the role of CYP2C9 SNPS on Acute Intermittent Porphyria manifestation. Abou Assali L, Gordillo D.M, Cerbino G, Varela L, Batlle A, Parera V, Rossetti MV. Medicina 77 (2017) Supl 1, 531, Res 1554.

Cerbino G, Varela L, Guolo M, Batlle A, Parera V, Rossetti MV. Porfiria dual PAI-PCT: mutación de novo en gen de la PBGD en paciente con Porfiria Cutánea Tardía hereditaria. J Basic Appl Genetics XXVIII (2017) Supp. Res GME16, 120.

Mode of action of two natural sesquiterpene lactones estafietin and eupatoriopicrin on Trypanosoma cruzi. Orlando G, Lombardo ME, Sülsen V. Medicina 77 (2017) Supl 1, 557, Res 1441.

Mitochondrial respiratory chain and Krebs cycle alterations due to porphyrinogenic agents in a mouse model of Acute Intermittent Porphyria. Zuccoli J, Martínez M del C, Ruspini S, Batlle A, Buzaleh AM. Medicina 77 (2017) Supl 1, 393, Res 1195.

MDR1 polymorphisms in HIV infected individuals. Its influence in Porphyria Cutanea Tarda triggering. Pagnotta P, Zuccoli J, Parera V, Rossetti MV, Lavandera J, Batlle A, Buzaleh AM, Melito V. Medicina 77 (2017), Supl 1, 262, Res 1934.

Análisis de polimorfismos del gen MDR1en la asociación entre Porfiria Cutánea Tardía y VIH. Pagnotta P, Zuccoli J, Melito V, Lavandera J, Parera V, Batlle A, Rossetti MV, Buzaleh AM. Basic Appl Genetics XXVIII (2017) Supp. Res GH3, 99.

Análisis de haplotipos de polimorfismos de nucleótido simple del CYP1A1 y CYP1A2. Su relación con el desencadenamiento de la Porfiria Cutánea Tardía. Gordillo D, Abou Assali L, Cerbino G, Varela L, Batlle A, Parera VE, Rossetti MV. Basic Appl. Genetics XXVIII (2017) Supp. Res GH14, 99.J

Actualización en el estudio de mutaciones en el gen HFE y su relacion con la Porfiria Cutánea Tardía en Argentina. Varela L, Cerbino G, Batlle A, Rossetti MV, Parera V. J Basic Appl. Genetics XXVIII (2017) Supp. Res GH2, 93.

Porphyrin photosensitization and reactive oxygen species scavengers protection in 5-aminolevulinic acid-based photodynamic therapy. Fukuda H, Teijo MJ, Martínez M del C. Batlle A. Medicina 76 (2016) 119, Res 92.

Triggering factors in Porphyria Cutanea Tarda Argentinean young women. Melito V, Winitzki P,  Batlle A; Rossetti MV, Parera V. Medicina 76 (2016) 115, Res 079.

Efecto del vanadato sobre la homeostasis del hierro en un modelo murino de diabetes tipo 1. Oliveri L, Mora S, Meiss R, Wald MR, Gerez E. Revista de la Sociedad Argentina de Diabetes 50 (Número Especial XX) (2016) 22, P14.

Gordillo M, Abou Assali L, Cerbino G, Varela L, Batlle AM, Parera V, Rossetti MV. The role of Cytochrome P450 isoenzymes on Porphyria Cutanea Tarda development. Medicina 76 (2016) 166, Res 253.

The effect of insulin growth factor on delta-aminolevulinic synthase expression. Mora S, Oliveri L, Parera V, Rossetti MV, Gerez E. Medicina 76 (2016) 158, Res 228.

Mitochondrial respiratory chain alterations due to porphyrinogenic agents in a mouse model of AcuteIntermittent Porphyria. Zuccoli J, Ruspini S, Batlle A, Martínez M del C, Buzaleh AM. Medicina 76 (2016) 119, Res 92.

Casos atipicos de heterocigosis compuesta en Porfiria Aguda Intermitente. C erbino GN, Varela LS, Guolo M, Batlle A, Parera VE, Rossetti MV. J. Basic Appl Genetics 26(1) (2015) Supp. Res GME25, 149.

Dos nuevos casos de coexistencia de Porfiria Variegata y Porfiria Cutanea Tardía. Melito VA, Cerbino G, Medina N, Granata BX, Guolo MN, Caballero FA, Batlle A, Rossetti MV, Parera VE. Medicina 75 (2015) Res 082, 76.

Efecto del ayuno sobre diferentes parámetros mitocondriales en animales controles y en un modelo de Porfiria Aguda Intermitente Zuccoli J, Ruspini S, Martínez M del C, Lavandera J, Batlle A, Buzaleh AM. Medicina 75 (2015) Res 326, 147.

Estudio de haplotipos del gen MDR1 en el desencadenamiento de la Porfiria Cutánea Tardía en individuos con VIH.  Zuccoli J, Melito V, Ruspini S, Rossetti MV, Parera V, Batlle A, Buzaleh AM. J Basic Appl Genetics 26(1) (2015) Supp. Res FG1, 93.

Fotoinactivación de bacterias Gram positivas a partir de una nueva porfirina sintética. Mamone L, Ferreira D, Di Venosa G, Vallecorsa P, Saenz D, Calvo G, Batlle A, Buzzola F, Durantini E, Casas A. Medicina 75 (2015) Res 037, 63.

Fotosensibilización de células tumorales empleando nuevos derivados meso-sustituidos de porfirinas. Vallecorsa P, Ferreyra D, Di Venosa G, Mamone L, Calvo G, Saenz D, Batlle A, Durantini E, Casas A. Medicina 75 (2015) Res 198, 109.

Implicancia de los polimorfismos del gen de resistencia a multidrogas (MDR1) en el desencadenamiento de la Porfiria Cutánea Tardía en individuos con VIH. Zuccoli J, Melito V, Lavandera J, Parera V, Batlle A, Rossetti MV, Buzaleh AM. Medicina 75 (2015) Res 69, 72.

Terapia fotodinámica con ácido 5-Aminolevúlico en cultivos tridimensionales de células de adenocarcinoma de pulmón. Fukuda H, Teijo MJ, Meiss R, Martínez M del C, Batlle A. Medicina 75 (2015) Res 529, 205.

Terapia fotodinámica inducida por ácido 5-aminolevulinico en células de adenocarcinoma mamario murino. Efecto del sulfuro de hidrógeno. Calvo G, Di Venosa G, Vallecorsa P, Mamone L, Batlle A, Casas A, Sáenz D. Medicina 75 (2015) Res 194, 108.

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